Shinichiro Oshima
Postdoctoral Fellow
Shinichiro Oshima earned his M.D. from Shiga University of Medical Science and a Ph.D. in Medicine from Kyoto University, where he conducted research under the mentorship of Dr. Akifumi Takaori and Dr. Ryo Yamamoto. His doctoral work focused on the heterogeneity and self-renewal mechanisms of hematopoietic stem cells, utilizing mouse, macaque, and human models with single-cell sequencing techniques. At the Aoki Lab, he aims to elucidate the mechanisms of the tumor microenvironment in lymphoid cancers to identify therapeutically relevant targets.
Yusuke Toda
Postdoctoral Fellow
Yusuke Toda earned his M.D. from Osaka City University and his Ph.D. in medicine from Kyoto University, where he conducted research under the mentorship of Dr. Akifumi Takaori and Dr. Kazuhiro Iwai. His doctoral research focused on the ubiquitin system, particularly the LUBAC ubiquitin ligase complex. At the Aoki Lab, he aims to integrate his clinical background with his expertise in molecular and cellular research to advance translational research that bridges fundamental discoveries and clinical applications.
Sierra Vanderkamp
PhD Student
Sierra Vanderkamp is a PhD student in the Department of Immunology at the University of Toronto. She earned her MSc from the University of Guelph, where her research focused on improving cancer immunotherapy by abrogating the off-target infection of T cells by oncolytic viruses. She later worked as a research technician at the UCL Cancer Institute, specializing in the development of patient-derived organoid models. In the Aoki Lab, Sierra investigates cancer-associated fibroblast (CAF) mediated resistance to CAR-T cell therapy in lymphoma, with the goal of improving therapeutic outcomes for patients.
Daniel Stueckmann
Senior Bioinformatician
Daniel Stueckmann received his BMSc from the University of Western Ontario specializing in Biochemistry and Cancer biology. He is now a PhD Candidate at the University of Toronto in the department of Molecular Genetics under the supervision of Dr. Gary Bader. His PhD research focused on multi-omic profiling of Renal Cell Carcinoma in collaboration with Dr. Keith Lawson, as well as benchmarking and parameter optimization of bulk RNA-seq deconvolution algorithms. He has also been involved in the characterization of humanized patient-derived xenograft models in collaboration with Dr. Laurie Ailles. At the Aoki lab, he aims to apply his knowledge of transcriptomic and proteomic technologies to the study of hematological malignancies such as Hodgkin's Lymphoma.
Putri Ramadani
Research Analyst I
Putri Ramadani is a Master's graduate in Medical Genomics at the University of Toronto with a strong passion and growing expertise in bioinformatics. At the Aoki Lab, she is involved in research focused on single-cell RNA sequencing and spatial transcriptomics to investigate the tumour microenvironment of Anaplastic Large Cell Lymphoma (ALCL), while also exploring other lymphoma subtypes across age groups. Her technical interests include building scalable and reproducible pipelines using R, command-line tools, and workflow managers such as Nextflow, with experience in high-performance computing (HPC) and cloud-based environments. Outside of her research, she actively curates her learning journey and self-initiated projects on GitHub.
Samran Prasla
Master Student
Samran Prasla is a Master's student in Medical Genomics at the University of Toronto and a Research Student in the Aoki Lab at Princess Margaret Cancer Centre, University Health Network (UHN). Her work focuses on computational analysis of circulating tumour DNA (ctDNA) data in classic Hodgkin lymphoma, including mutational profiling, copy number analysis, molecular classification, and minimal residual disease (MRD) detection. Her interests lie at the intersection of cancer genomics, computational biology, and translational medicine, with a focus on applying genomics to improve disease monitoring and precision oncology.
Hammad Umar
Summer Research Student
Hammad Umar earned his BSc from the University of Toronto, majoring in Human Biology with minors in Immunology and Physiology. His academic background has led him to develop a strong interest in cancer immunology and lymphoma biology. At the Aoki Lab, he is investigating the functional role of key driver gene mutations in Hodgkin Lymphoma with a focus on understanding how these mutations contribute to oncogenic signaling and treatment resistance. His work involves cell culture, flow cytometry, with plans to extend into CRISPR & prime editing and humanized mouse models to further elucidate the impact of these alterations on both tumor cells and the tumor microenvironment. Outside of research, Hammad enjoys playing soccer.